Skene's duct cyst in a newborn: case report and review of the literature.

The diagnosis of a rare Skene's duct cyst in a newborn was made based on its location in relation to the urethra and the demonstration of transitional epithelium in the cyst wall. A through urologic evaluation was required to differentiate it from an ectopic ureterocele, urethrocele, urethral diverticula, and benign or malignant urethral and paraurethral tumors. Other uncommon vaginal cysts may be of müllerian duct origin and lined with stratified squamous epithelium or from persistent mesonephric (Gartner's) ducts and lined with columnar epithelium. Many cysts drain spontaneously but if treatment is indicated, marsupialization or simple transvaginal excision usually is adequate.