Menegozzo M, Belli S, Bruno C, Canfora V, Costigliola A, Di Cintio P, Di Liello L, Grignoli M, Palumbo F, Sapio P
Istituto di Medicina del Lavoro, Primo Policlinico, Napoli.
Med Lav. 1993 May-Jun;84(3):193-200.
A study was made of the mortality experience of a cohort of railway carriage construction workers with the aim of detecting asbestos-induced disease. The cohort included 1534 men who were active as at 01.01.1970 and/or hired up to 30.06.89. Vital status was ascertained for 97.7% of the cohort. The mortality experience of the cohort was compared with that of the population of the Campania Region. Altogether, 194 deaths were observed (SMR: 0.88). Significant mortality deficits were associated with circulatory causes (SMR: 0.64, 58 observed), non-malignant respiratory causes (SMR: 0.59, 12 observed), and accidents (SMR: 0.39, 5 observed). A significant increase in mortality from all neoplasms was detected (SMR: 1.25, 69 observed), mainly due to an excess of lung cancer (SMR: 1.45, 28 observed), pleural cancer (SMR: 4.72, 3 observed), and peritoneal cancer (SMR: 7.47, 2 observed). The excess of mortality from respiratory neoplasms mainly affected subjects who had started employment more than 20 years previously.
为了检测石棉诱发疾病，对一组铁路车厢建造工人的死亡情况进行了研究。该队列包括1534名男性，他们在1970年1月1日时在职和/或截至1989年6月30日被雇佣。确定了该队列中97.7%人员的生命状态。将该队列的死亡情况与坎帕尼亚地区的人口死亡情况进行了比较。总共观察到194例死亡（标准化死亡比：0.88）。显著的死亡不足与循环系统病因（标准化死亡比：0.64，观察到58例）、非恶性呼吸道病因（标准化死亡比：0.59，观察到12例）和事故（标准化死亡比：0.39，观察到5例）相关。检测到所有肿瘤的死亡率显著增加（标准化死亡比：1.25，观察到69例），主要是由于肺癌（标准化死亡比：1.45，观察到28例）、胸膜癌（标准化死亡比：4.72，观察到3例）和腹膜癌（标准化死亡比：7.47，观察到2例）过多。呼吸道肿瘤导致的死亡率过高主要影响那些20多年前就开始工作的人。
