Ikeda D M, Helvie M A, Frank T S, Chapel K L, Andersson I T
Department of Radiology, University of Michigan Hospitals, Ann Arbor.
Radiology. 1993 Oct;189(1):89-94. doi: 10.1148/radiology.189.1.8396786.
To correlate the range of clinical presentations with mammographic and histologic findings in patients with Paget disease of the nipple.
The clinical, pathologic, and mammographic records of 58 patients who had biopsy-proved Paget disease of the nipple were retrospectively reviewed. The results of two previous studies were also included.
Among 34 patients who had typical findings of Paget disease, the mammograms of 17 (50%) showed normal findings, those of 10 (29%) showed nipple, areolar, or subareolar abnormalities, and those of seven (21%) showed evidence of masses or calcifications. Of the mammograms of 24 women with Paget disease but without clinical findings, 19 (79%) showed evidence of suspicious masses or calcifications, four (17%) showed nipple or areolar abnormalities, and one was negative.
Nonspecific findings of nipple-areolar complex thickening should be correlated with findings at breast physical examination to confirm or exclude Paget disease.
将乳头派杰病患者的临床表现范围与乳房X线摄影及组织学检查结果相关联。
回顾性分析58例经活检证实为乳头派杰病患者的临床、病理及乳房X线摄影记录。还纳入了之前两项研究的结果。
在34例有典型乳头派杰病表现的患者中，17例（50%）乳房X线摄影显示正常，10例（29%）显示乳头、乳晕或乳晕下异常，7例（21%）显示有肿块或钙化迹象。在24例有乳头派杰病但无临床表现的女性乳房X线摄影中，19例（79%）显示有可疑肿块或钙化迹象，4例（17%）显示乳头或乳晕异常，1例为阴性。
乳头-乳晕复合体增厚的非特异性表现应与乳房体格检查结果相关联，以证实或排除派杰病。
