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肝细胞癌手术切除的结果。

Results of surgical resection for hepatocellular carcinoma.

作者信息

Closset J, Gelin M, el Nakadi I, Van de Stadt J, Lambilliotte J P

机构信息

Service de Chirurgie Digestive, Hôpital Erasme, Université Libre de Bruxelles, Belgique.

出版信息

Acta Chir Belg. 1993 May-Jun;93(3):98-101.

PMID:8396830
Abstract

During the past 13-years, 35 patients with hepatocellular carcinoma (HCC) were treated by hepatic resection. There were 11 females and 24 males, the age ranged from 17 to 82 years with a mean of 59 years. HCC was associated with liver cirrhosis in 17 patients (48%). Fifteen patients underwent a major hepatectomy, 18 patients a partial hepatectomy (single or bisegmentectomy) and 2 patients had a wedge resection. One patient presenting with a spontaneous tumor rupture died immediately after surgery. Out of the 34 others, 3 died in the postoperative period (8.8%). Early complications occurred in 57% of the patients. The actuarial 5-years survival rate is 30%. The only prognostic factor is tumor extension to a single or both lobes. A significant difference in the survival rate has been observed between patients with or without underlying cirrhosis. Our experience suggest that long-term survival can be expected after surgical resection for HCC.

摘要

在过去13年中,35例肝细胞癌(HCC)患者接受了肝切除术。其中女性11例,男性24例,年龄范围为17至82岁,平均年龄59岁。17例患者(48%)的HCC与肝硬化有关。15例患者接受了肝大部切除术,18例患者接受了部分肝切除术(单段或双段切除术),2例患者进行了楔形切除术。1例出现自发性肿瘤破裂的患者术后立即死亡。在其他34例患者中,3例在术后死亡(8.8%)。57%的患者发生了早期并发症。5年实际生存率为30%。唯一的预后因素是肿瘤扩展至一个或两个肝叶。有无潜在肝硬化的患者之间生存率存在显著差异。我们的经验表明,HCC手术切除后有望获得长期生存。

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