[Nucleotide sequence and genome structure of mink enteritis virus].

This paper reports the sequence of the cloned mink enteritis virus (MEV) RF DNA and its 3' end and 5' end structure predicted. MEV genome is near 5064 nucleotides (nt) in length. In its 5' end non-coding region, there are three 51 nt repeated sequences. The nucleotide sequence of MEV genome has very high homology with those of canine parvovirus (CPV) and feline parvovirus (FPV), reaching 99.1% and 99.9% respectively in the structure gene region. But they differ notably in 5' end non-coding region. The structure of MEV genome is almost same as those of CPV and FPV. It has two large open reading frames which code for 668 and 722 amino acids respectively. There are two promoters at map unit 37 and 39. At map unit 97, there is a poly A site. All the mRNAs of NS2, VP1 and VP2 are spliced.