考试应激期间及之后社会支持与[3H]丙咪嗪结合的关系。
Relationship of social support to [3H]imipramine binding during and after examination stress.
作者信息
Iny L J, Suranyi-Cadotte B E, Bernier B, Luthe L, Meaney M J
机构信息
Douglas Hospital Research Centre, Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
出版信息
J Psychiatry Neurosci. 1993 Jul;18(4):143-7.
The relationship between social support, depressive symptoms and the maximal binding capacity of [3H]imipramine (Bmax) in platelets was examined in medical students during and after a period of examination stress. There was a positive correlation between the students' perception of their social support and [3H]imipramine Bmax values during examinations, and their perception of social support contributed significantly to the prediction of Bmax by depressive symptomatology. The results suggest that psychosocial factors may be associated with alterations in serotonergic neurotransmission, rendering an individual more physiologically vulnerable to psychological disturbances.
在一段考试压力期间及之后，对医科学生的社会支持、抑郁症状与血小板中[3H]丙咪嗪最大结合能力（Bmax）之间的关系进行了研究。在考试期间，学生对社会支持的感知与[3H]丙咪嗪Bmax值之间存在正相关，且他们对社会支持的感知对抑郁症状学预测Bmax有显著贡献。结果表明，心理社会因素可能与血清素能神经传递的改变有关，使个体在生理上更容易受到心理干扰。
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