Manor R S, Livni E, Cohen S
Invest Ophthalmol Vis Sci. 1979 Feb;18(2):204-6.
An immunological basis for neurological involvement in Vogt-Koyanagi-Harada syndrome was sought by means of the migration-inhibition factor technique with human myelin basic protein. The test was carried out in four patients who had recent manifestations of the syndrome, two of whom were evaluated both before and after initiation of steroid treatment; in one patient 4 years after recovery from the syndrome; in three patients having uveitis of other causes, and in 12 healthy controls. The results were positive in all four patients who had recent manifestations, whereas they were negative in all the others. This finding may constitute evidence of a cell-mediated immunity toward components of the nervous system in this disease entity.
通过人髓鞘碱性蛋白迁移抑制因子技术，探寻伏格特-小柳-原田综合征神经受累的免疫学基础。对4例近期有该综合征表现的患者进行了此项检测，其中2例在开始使用类固醇治疗前后均进行了评估；1例在综合征恢复4年后进行检测；3例患有其他原因葡萄膜炎的患者以及12名健康对照者也接受了检测。所有近期有综合征表现的4例患者检测结果均为阳性，而其他所有人的检测结果均为阴性。这一发现可能构成了针对该疾病实体中神经系统成分的细胞介导免疫的证据。
