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对献血者进行1型人类免疫缺陷病毒抗体筛查。

Screening of blood donors for antibody to human immunodeficiency virus type 1.

作者信息

Acquaye J K

机构信息

National Blood Transfusion Service, Korle Bu Ghana.

出版信息

West Afr J Med. 1993 Apr-Jun;12(2):93-5.

PMID:8398939
Abstract

29,575 blood donors of whom about 20% were voluntary were screened for HIV 1. During the three years period 1988 to 1990 four different tests kits were used. Three were ELISA methods and one an agglutination method. Comparison of the monthly seropositivity for each year showed variations of 0.9 to 4.4% for the first year, 1.4 to 10% for the second year and 0.2 to 6.9% for the third year. The differences in the standard errors were found to be significant. These wide differences are suggested to be due to many factors including the use of different screening kits, many first time donors and inability to perform repeat tests on positive samples.

摘要

对29575名献血者进行了HIV 1筛查,其中约20%为自愿献血者。在1988年至1990年的三年期间,使用了四种不同的检测试剂盒。三种是酶联免疫吸附测定(ELISA)方法,一种是凝集法。每年每月血清阳性率的比较显示,第一年为0.9%至4.4%,第二年为1.4%至10%,第三年为0.2%至6.9%。标准误差的差异被发现具有显著性。这些巨大差异被认为是由多种因素造成的,包括使用不同的筛查试剂盒、许多首次献血者以及无法对阳性样本进行重复检测。

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