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携带人类免疫缺陷病毒抗体的献血者的流行病学特征:泰国

Epidemiologic characteristics of blood donors with antibody to human immunodeficiency virus: Thailand.

作者信息

Nuchprayoon C, Tanprasert S, Chumnijarakij T, Thanomchat S, O'Prasert B, Adulwijit S

机构信息

National Blood Center, Thai Red Cross Society, Bangkok, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 1995 Mar;26(1):98-103.

PMID:8525427
Abstract

Of 782,190 volunteer blood donors in Bangkok and nearby areas, who were screened for infection with human immunodeficiency type 1 (HIV-1) from January 1988 through December 1992, 3,219 tested positive on both enzyme immuno assay and Western blot assay. The identification variables of the donor were collected. The majority of HIV seropositive blood donors were male. The average age (median) of HIV seropositive was 26-29 years all through 1988-2992. The prevalence of HIV seropositive in male donors was higher than that in females. HIV seropositivity was confirmed in blood donations from first-time male donors in this study during 1988-1992. This rate has increased progressively from 0.87/1,000 in 1988 to 15.95/1,000 in 1992 with much higher rates in repeat donors. The repeat male donors increased from 0.77/1,000 in 1988 to 5.26/1,000 in 1991 and since then showed a decreased rate to 3.93/1,000 in 1992. Female donors were infected with HIV more frequently with the prevalence by sex ratio M:F rising from 27:1 in 1988 to 6.6:1 in 1992. Comparing the seropositive rate between first time and repeat female donors, the results showed an increase in rate from 0.11/1,000 in 1990 to 2.02/1,000 in 1992, but essentially the same rate in report donors. A majority of HIV seropositive blood donors (1990-1992) lived in Bangkok (42-49%) and among those who lived in one eastern province (Samut Prakan), 90-93% lived in the industrial areas. Of those who lived in Chon Buri Province, 73-88% lived in Sattaheep District, which is a naval base.

摘要

在1988年1月至1992年12月期间,对曼谷及周边地区的782,190名志愿献血者进行了1型人类免疫缺陷病毒(HIV-1)感染筛查,其中3219人在酶免疫测定和蛋白质印迹测定中均呈阳性。收集了献血者的识别变量。大多数HIV血清阳性献血者为男性。1988 - 1992年期间,HIV血清阳性者的平均年龄(中位数)为26 - 29岁。男性献血者中HIV血清阳性的患病率高于女性。在本研究中,1988 - 1992年期间首次男性献血者的血液中证实了HIV血清阳性。这一比率从1988年的0.87/1000逐渐上升至1992年的15.95/1000,重复献血者的比率更高。重复男性献血者从1988年的0.77/1000增加到1991年的5.26/1000,此后在1992年降至3.93/1000。女性献血者感染HIV的频率更高,男女患病率之比从1988年的27:1上升至1992年的6.6:1。比较首次和重复女性献血者的血清阳性率,结果显示该比率从1990年的0.11/1000增加到1992年的2.02/1000,但重复献血者的比率基本相同。大多数HIV血清阳性献血者(1990 - 1992年)居住在曼谷(42 - 49%),在居住在东部一个省份(北榄府)的人中,90 - 93%居住在工业区。在春武里府居住的人中,73 - 88%居住在梭桃邑区,这是一个海军基地。

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