Segato T, Midena E, Blarzino M C
Institute of Ophthalmology, University of Padova, Italy.
Aging (Milano). 1993 Jun;5(3):165-76. doi: 10.1007/BF03324151.
Age-related macular degeneration (AMD), a bilateral, progressive macular disease, represents the major cause of blindness among elderly people living in Western countries. Clinical features of AMD vary from the initial asymptomatic aspects, drusen and retinal pigment epithelium alterations, to severe atrophic or exudative changes in the advanced stages, characterized by the irreversible decrease of visual function. Current epidemiologic, pathogenetic and clinical data are reviewed, and the importance of the exact identification of patients at risk of evolution toward the exudative form is addressed. The therapeutic approach to AMD is also analyzed and the role of laser photocoagulation is discussed.
年龄相关性黄斑变性（AMD）是一种双侧进行性黄斑疾病，是西方国家老年人失明的主要原因。AMD的临床特征各不相同，从最初无症状的表现、玻璃膜疣和视网膜色素上皮改变，到晚期严重的萎缩性或渗出性改变，其特点是视功能不可逆下降。本文综述了当前的流行病学、发病机制和临床数据，并阐述了准确识别有发展为渗出性形式风险患者的重要性。还分析了AMD的治疗方法，并讨论了激光光凝的作用。
