Verrina E, Perfumo F, Zacchello G, Edefonti A, Bassi S, Capasso G, Caringella D A, Castellani A, Longo L, Rinaldi S
Nephrology Department, G. Gaslini Institute, Genova, Italy.
Perit Dial Int. 1993;13 Suppl 2:S254-6.
During the period 1986-1991, 140 pediatric patients [age < or = 15 years at the start of chronic peritoneal dialysis (CPD)], belonging to 15 dialysis centers, were enrolled in the Italian Registry of Pediatric Chronic Peritoneal Dialysis. Data on 188 peritoneal catheters were collected: 161 catheters were Tenckhoff (144 double-cuff, 17 single-cuff), and 27 were two-cuff Valli-type catheters. All catheters were surgically inserted; the entry site was in the midline in 84 cases and paramedian in 104. An omentectomy was performed in 78.8% of the cases. Apart from peritonitis, there were 161 catheter-related complications (103 exit-site infections, 17 leakages, 15 obstructions, 15 outer-cuff extrusions, 5 hemoperitoneum, 6 others) observed during 2687.5 dialysis-months, with an incidence of one complication every 16.7 dialysis-months. Fifty-five catheters (29.2%) were removed; infection (39 cases) was the main cause for removal, followed by obstruction (9 cases), dislocation, and outer-cuff extrusion (2 cases each). Actuarial survival of all catheters was 79.7% at 1 year, 66.6% at 2 years, 42.8% at 3 years, and 39.8% at 4 years. No difference in catheter survival was observed according to the entry site. When considering the age of the patients at catheter insertion, a difference close to statistical significance was found (p = 0.06).
在1986年至1991年期间,来自15个透析中心的140名儿科患者(慢性腹膜透析开始时年龄≤15岁)被纳入意大利儿科慢性腹膜透析登记处。收集了188根条8根腹膜导管的数据:161根导管为Tenckhoff导管(144根双套囊,17根单套囊),27根为双套囊Valli型导管。所有导管均通过手术插入;84例入路部位在中线,104例在旁正中。78.8%的病例进行了网膜切除术。除腹膜炎外,在2687.5个透析月期间观察到161例与导管相关的并发症(103例出口处感染、17例渗漏、15例梗阻、15例外套管挤出、5例腹腔积血、6例其他),并发症发生率为每16.7个透析月1例。55根导管(29.2%)被拔除;感染(39例)是拔除的主要原因,其次是梗阻(9例)、移位和外套管挤出(各2例)。所有导管的1年精算生存率为79.7%,2年为66.6%,3年为42.8%,4年为39.8%。根据入路部位未观察到导管生存率的差异。考虑到导管插入时患者的年龄,发现差异接近统计学意义(p = 0.06)。