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慢性腹膜透析儿科患者群体并发症分析。意大利儿科慢性腹膜透析登记处。

Analysis of complications in a chronic peritoneal dialysis pediatric patient population. The Italian Registry of Pediatric Chronic Peritoneal Dialysis.

作者信息

Verrina E, Bassi S, Perfumo F, Edefonti A, Zacchello G, Andreetta B, Pela I, Penza R, Piaggio G, Picca M

机构信息

Nephrology Department, G. Gaslini Institute, Genova, Italy.

出版信息

Perit Dial Int. 1993;13 Suppl 2:S257-9.

PMID:8399582
Abstract

During the period 1986-1991, the Italian Registry of Pediatric Chronic Peritoneal Dialysis collected data from 140 patients younger than 15 years at the start of chronic peritoneal dialysis (CPD). In this study we review the Registry's complications and patient hospitalization data. A total of 395 complications directly related to CPD were registered during 2722 dialysis-months. There were 176 episodes of peritonitis (44.5%), 161 catheter-related complications (40.7%) (103 exit-site infections, 17 leakages, 15 obstructions, 15 cuff extrusions, 5 hemoperitoneum, and 6 other complications), and 58 technique-related complications (14.8%) (39 abdominal hernias, 10 hydroceles, 5 with abdominal pain, 4 hydrothorax complications). The patient hospitalization rate during the period 1989-1991 was evaluated; the analysis referred to 106 patients who underwent treatment for a total of 1520.5 dialysis-months. Patients starting CPD in the year and patients already on CAPD spent 5.8 and 2.1 days per patient-month in the hospital, respectively; the difference was not statistically significant. The evaluation of complications (both technical and systemic) causing patient hospitalization showed that peritonitis was responsible for 43.2% of patient admissions and 36.3% of days hospitalized, catheter-related complications for 22% and 19.8%, technique-related complications for 8.3% and 5.1%, and other clinical complications for 26.5% and 38.8%, respectively.

摘要

1986年至1991年期间,意大利儿科慢性腹膜透析登记处收集了140例开始慢性腹膜透析(CPD)时年龄小于15岁患者的数据。在本研究中,我们回顾了登记处的并发症和患者住院数据。在2722个透析月期间,共记录了395例与CPD直接相关的并发症。其中有176例腹膜炎(44.5%),161例导管相关并发症(40.7%)(103例出口处感染、17例渗漏、15例梗阻、15例袖套挤出、5例腹腔积血和6例其他并发症),以及58例技术相关并发症(14.8%)(39例腹壁疝、10例鞘膜积液、5例腹痛、4例胸腔积液并发症)。评估了1989年至1991年期间患者的住院率;分析涉及106例接受治疗的患者,总计1520.5个透析月。当年开始CPD的患者和已经接受持续性非卧床腹膜透析(CAPD)的患者每月分别住院5.8天和2.1天;差异无统计学意义。对导致患者住院的并发症(技术和全身并发症)评估显示,腹膜炎分别导致43.2%的患者入院和36.3%的住院天数,导管相关并发症导致22%和19.8%,技术相关并发症导致8.3%和5.1%,其他临床并发症导致26.5%和38.8%。

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