在一次与3型轮状病毒相关的严重马驹腹泻疫情中一种次要的流行毒株。

A minor prevalent strain in a severe outbreak of foal diarrhea associated with serotype 3 rotavirus.

作者信息

Takagi M, Hoshi A, Ohta C, Shirahata T, Goto H, Urasawa T, Taniguchi K, Urasawa S

机构信息

Department of Veterinary Microbiology, Obihiro University of Agriculture and Veterinary Medicine, Japan.

出版信息

J Vet Med Sci. 1993 Aug;55(4):661-3. doi: 10.1292/jvms.55.661.

DOI:10.1292/jvms.55.661

PMID:8399751

Abstract

An epizootic of foal diarrhea due to serotype 3 rotavirus (RV) was observed in 89 of 168 cases (53%) during the period from March to July in 1987. A total of 51 strains of RV were isolated from the 62 diarrheal feces examined, and one isolate (CH-3) showed a unique electropherotype of viral RNA which differed from the others that widely prevailed on this farm. No positive reaction was observed between strain CH-3 and each of the antisera against serotypes 1 to 12 of human and animal RV in neutralization tests. However, dsRNAs of the CH-3 virus were hybridized with a probe prepared from a strain of equine serotype 3 RV.

摘要

1987年3月至7月期间，在168例病例中的89例（53%）观察到由3型轮状病毒（RV）引起的马驹腹泻流行。从62份腹泻粪便样本中总共分离出51株RV，其中一株分离株（CH-3）显示出独特的病毒RNA电泳图谱型，与该农场广泛流行的其他分离株不同。在中和试验中，CH-3株与针对人和动物RV 1至12型的每种抗血清之间均未观察到阳性反应。然而，CH-3病毒的双链RNA与从一株马3型RV制备的探针杂交。