Yamada T, Moralejo D, Tsuchiya K, Agui T, Matsumoto K
Institute for Animal Experimentation, University of Tokushima School of Medicine, Japan.
J Vet Med Sci. 1993 Aug;55(4):673-5. doi: 10.1292/jvms.55.673.
The investigation of biochemical markers in wild rats (Rattus norvegicus) is thought to be useful in the efficient establishment of inbred strains with a wide range of genetic variability of wild rats. In this study, 21 marker proteins were analyzed by electrophoresis in nine wild rats captured in Oita city. It was found that eleven marker samples in six animals were heterogeneous. We further found that the investigated wild rat population possessed the interesting polymorphisms of esterase-4 (ES-4) with high frequency, which are very rare in laboratory rats.
对野生大鼠（褐家鼠）生化标记的研究被认为有助于高效建立具有广泛遗传变异性的野生大鼠近交系。在本研究中，对在大分市捕获的9只野生大鼠进行了电泳分析，检测了21种标记蛋白。结果发现，6只动物中的11个标记样本具有异质性。我们进一步发现，所研究的野生大鼠群体中酯酶-4（ES-4）具有高频率的有趣多态性，这在实验室大鼠中非常罕见。
