An ATP- and hsc70-dependent oligomerization of nascent heat-shock factor (HSF) polypeptide suggests that HSF itself could be a "sensor" for the cellular stress response.
作者信息
Schlesinger M J, Ryan C
机构信息
Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110.
出版信息
Protein Sci. 1993 Aug;2(8):1356-60. doi: 10.1002/pro.5560020819.
Abstract
摘要
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本文引用的文献
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Molecular weight estimations of proteins by electrophoresis in polyacrylamide gels of graded porosity.通过在梯度孔隙率聚丙烯酰胺凝胶中进行电泳来估计蛋白质的分子量。
FEBS Lett. 1972 Feb 1;20(2):199-202. doi: 10.1016/0014-5793(72)80793-2.
2
Regulation of heat shock factor trimer formation: role of a conserved leucine zipper.热休克因子三聚体形成的调控：保守亮氨酸拉链的作用。
Science. 1993 Jan 8;259(5092):230-4. doi: 10.1126/science.8421783.
3
The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels.热休克反应在转录和转录后水平上都是自我调节的。
Cell. 1982 Dec;31(3 Pt 2):593-603. doi: 10.1016/0092-8674(82)90315-4.
4
Post-translational insertion of a fragment of the glucose transporter into microsomes requires phosphoanhydride bond cleavage.葡萄糖转运蛋白片段在微粒体中的翻译后插入需要磷酸酐键断裂。
Nature. 1986;322(6079):549-52. doi: 10.1038/322549a0.
5
Induction of sequence-specific binding of Drosophila heat shock activator protein without protein synthesis.果蝇热休克激活蛋白序列特异性结合的诱导，无需蛋白质合成。
Nature. 1987;327(6124):727-30. doi: 10.1038/327727a0.
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Activation in vitro of sequence-specific DNA binding by a human regulatory factor.一种人类调节因子在体外对序列特异性DNA结合的激活作用。
Nature. 1988 Sep 22;335(6188):372-5. doi: 10.1038/335372a0.
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Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.人类细胞中热休克元件结合活性与HSP70基因转录率的协同变化。
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