• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
An ATP- and hsc70-dependent oligomerization of nascent heat-shock factor (HSF) polypeptide suggests that HSF itself could be a "sensor" for the cellular stress response.新生热休克因子（HSF）多肽的一种依赖于ATP和hsc70的寡聚化表明，HSF自身可能是细胞应激反应的一个“传感器”。
Protein Sci. 1993 Aug;2(8):1356-60. doi: 10.1002/pro.5560020819.
2
Activation of Drosophila heat shock factor: conformational change associated with a monomer-to-trimer transition.果蝇热休克因子的激活：与单体到三聚体转变相关的构象变化。
Mol Cell Biol. 1993 Jun;13(6):3481-6. doi: 10.1128/mcb.13.6.3481-3486.1993.
3
Dynamic association of transcriptional activation domains and regulatory regions in Saccharomyces cerevisiae heat shock factor.酿酒酵母热休克因子中转录激活结构域与调控区域的动态关联
Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1200-5. doi: 10.1073/pnas.032681299. Epub 2002 Jan 29.
4
Modulation of Drosophila heat shock transcription factor activity by the molecular chaperone DROJ1.分子伴侣DROJ1对果蝇热休克转录因子活性的调节
EMBO J. 2001 Feb 1;20(3):499-509. doi: 10.1093/emboj/20.3.499.
5
Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia.培养的成肌细胞中应激蛋白的诱导。缺血期间热休克转录因子激活的分子信号。
J Clin Invest. 1992 May;89(5):1685-9. doi: 10.1172/JCI115768.
6
Stress-induced oligomerization and chromosomal relocalization of heat-shock factor.
Nature. 1991 Oct 31;353(6347):822-7. doi: 10.1038/353822a0.
7
The heat shock transcription factor in liver exists in a form that has DNA binding activity but no transcriptional activity.肝脏中的热休克转录因子以一种具有DNA结合活性但无转录活性的形式存在。
Biochem Biophys Res Commun. 1994 Jun 15;201(2):552-8. doi: 10.1006/bbrc.1994.1737.
8
A stress regulatory network for co-ordinated activation of proteasome expression mediated by yeast heat shock transcription factor.由酵母热休克转录因子介导的蛋白酶体表达协同激活的应激调节网络。
Mol Microbiol. 2006 Apr;60(1):240-51. doi: 10.1111/j.1365-2958.2006.05097.x.
9
Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.热休克蛋白70（Hsp 70）与新合成蛋白质的相互作用：对蛋白质折叠和组装的影响。
Science. 1990 May 18;248(4957):850-4. doi: 10.1126/science.2188360.
10
Heat shock factor-1 and the heat shock cognate 70 protein associate in high molecular weight complexes in the cytoplasm of NIH-3T3 cells.热休克因子-1与热休克同源蛋白70在NIH-3T3细胞的细胞质中以高分子量复合物的形式结合。
Biochem Biophys Res Commun. 1995 Aug 4;213(1):1-6. doi: 10.1006/bbrc.1995.2090.

引用本文的文献

1
Exploration of the truncated cytosolic Hsp70 in plants - unveiling the diverse T1 lineage and the conserved T2 lineage.植物中截短型胞质热休克蛋白70的探索——揭示多样的T1谱系和保守的T2谱系
Front Plant Sci. 2023 Nov 16;14:1279540. doi: 10.3389/fpls.2023.1279540. eCollection 2023.
2
Heat Shock Factor Is Involved in Regulating the Transcriptional Expression of Two Potential Hsps ( and ) and Its Role in Heat Shock Response of .热休克因子参与调控两种潜在热休克蛋白（和）的转录表达及其在热休克反应中的作用。
Front Physiol. 2020 Sep 15;11:562204. doi: 10.3389/fphys.2020.562204. eCollection 2020.
3
Small molecule activators of the heat shock response: chemical properties, molecular targets, and therapeutic promise.热休克反应小分子激活剂：化学性质、分子靶标和治疗前景。
Chem Res Toxicol. 2012 Oct 15;25(10):2036-53. doi: 10.1021/tx300264x. Epub 2012 Jul 31.
4
Dual regulation of heat-shock transcription factor (HSF) activation and DNA-binding activity by H2O2: role of thioredoxin.过氧化氢对热休克转录因子（HSF）激活和DNA结合活性的双重调节：硫氧还蛋白的作用
Biochem J. 1996 Aug 15;318 ( Pt 1)(Pt 1):187-93. doi: 10.1042/bj3180187.
5
Interaction between heat shock factor and hsp70 is insufficient to suppress induction of DNA-binding activity in vivo.热休克因子与hsp70之间的相互作用不足以在体内抑制DNA结合活性的诱导。
Mol Cell Biol. 1994 Oct;14(10):6552-60. doi: 10.1128/mcb.14.10.6552-6560.1994.

本文引用的文献

1
Molecular weight estimations of proteins by electrophoresis in polyacrylamide gels of graded porosity.通过在梯度孔隙率聚丙烯酰胺凝胶中进行电泳来估计蛋白质的分子量。
FEBS Lett. 1972 Feb 1;20(2):199-202. doi: 10.1016/0014-5793(72)80793-2.
2
Regulation of heat shock factor trimer formation: role of a conserved leucine zipper.热休克因子三聚体形成的调控：保守亮氨酸拉链的作用。
Science. 1993 Jan 8;259(5092):230-4. doi: 10.1126/science.8421783.
3
The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels.热休克反应在转录和转录后水平上都是自我调节的。
Cell. 1982 Dec;31(3 Pt 2):593-603. doi: 10.1016/0092-8674(82)90315-4.
4
Post-translational insertion of a fragment of the glucose transporter into microsomes requires phosphoanhydride bond cleavage.葡萄糖转运蛋白片段在微粒体中的翻译后插入需要磷酸酐键断裂。
Nature. 1986;322(6079):549-52. doi: 10.1038/322549a0.
5
Induction of sequence-specific binding of Drosophila heat shock activator protein without protein synthesis.果蝇热休克激活蛋白序列特异性结合的诱导，无需蛋白质合成。
Nature. 1987;327(6124):727-30. doi: 10.1038/327727a0.
6
Activation in vitro of sequence-specific DNA binding by a human regulatory factor.一种人类调节因子在体外对序列特异性DNA结合的激活作用。
Nature. 1988 Sep 22;335(6188):372-5. doi: 10.1038/335372a0.
7
Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.人类细胞中热休克元件结合活性与HSP70基因转录率的协同变化。
Mol Cell Biol. 1988 Nov;8(11):4736-44. doi: 10.1128/mcb.8.11.4736-4744.1988.
8
Germline transformation used to define key features of heat-shock response elements.种系转化用于定义热休克反应元件的关键特征。
Science. 1988 Mar 4;239(4844):1139-42. doi: 10.1126/science.3125608.
9
An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein.内质网中一种热休克蛋白70样蛋白：与78kd葡萄糖调节蛋白及免疫球蛋白重链结合蛋白的一致性。
Cell. 1986 Jul 18;46(2):291-300. doi: 10.1016/0092-8674(86)90746-4.
10
Speculations on the functions of the major heat shock and glucose-regulated proteins.关于主要热休克蛋白和葡萄糖调节蛋白功能的推测。
Cell. 1986 Sep 26;46(7):959-61. doi: 10.1016/0092-8674(86)90693-8.

An ATP- and hsc70-dependent oligomerization of nascent heat-shock factor (HSF) polypeptide suggests that HSF itself could be a "sensor" for the cellular stress response.

作者信息

Schlesinger M J, Ryan C

机构信息

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110.

出版信息

Protein Sci. 1993 Aug;2(8):1356-60. doi: 10.1002/pro.5560020819.

DOI:10.1002/pro.5560020819
PMID:8401220
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2142440/
Abstract
摘要