[经皮肾手术后的甘氨酸中毒]

[Glycine poisoning after percutaneous kidney surgery].

作者信息

Tauzin-Fin P, Krol-Houdek M C, Saumtally S, Muscagorry J M

机构信息

Département d'Anesthésie-Réanimation III, Hôpital Pellegrin-Tondu, Bordeaux, France.

出版信息

Can J Anaesth. 1993 Sep;40(9):866-9. doi: 10.1007/BF03009259.

DOI:10.1007/BF03009259

PMID:8403181

Abstract

We describe two cases of altered consciousness associated with nausea and vomiting after renal surgery. These events occurred respectively one and two hours after surgery. They are believed to be caused by the transfer of large amounts of irrigating solution containing glycine 1.5%. The effects of hyponatraemia (132 and 129 mmol.L-1) and glycinaemia (3518 and 8589 mmol.L-1) are discussed. We conclude on the importance of an early clinical diagnosis completed by biological investigation to allow an adequate symptomatic management.

摘要

我们描述了两例肾手术后出现意识改变并伴有恶心和呕吐的病例。这些事件分别发生在术后1小时和2小时。据信它们是由大量含1.5%甘氨酸的冲洗液转移所致。讨论了低钠血症（132和129 mmol/L）和甘氨酸血症（3518和8589 mmol/L）的影响。我们得出结论，早期临床诊断结合生物学检查对于进行适当的对症治疗非常重要。