Sasaki A, Horiuchi N, Hasegawa K, Uehara M
Osaka Medical Center for Adulthood Disease, Japan.
Diabetes Res Clin Pract. 1993 Jun;20(3):241-6. doi: 10.1016/0168-8227(93)90084-i.
To determine the accuracy of the stated causes of death in diabetic patients, we analyzed 503 death certificates of diabetic patients who had been followed up for 9.4 years on average at Osaka Medical Center for Adulthood Diseases and had died during the observation period from 1960 to 1984. Of the certificates examined, only 213 (42.4%) mentioned diabetes, either as the underlying cause or as a contributory condition. The proportion of certificates that mentioned diabetes was related to the underlying cause of death; it was 18.7% for malignant neoplasms, 40.5% for cerebrovascular disease and 46.9% for disease of the heart, while it was 81.8% for renal disease. The proportion was higher for females (48.7%) than for males (39.5%), and a significant difference was observed between the sexes in the proportion in the case of disease of the heart. The proportion was not related to any significant extent to the year of death or the age at death. However, it was related to fasting plasma glucose (FPG) level and type of treatment. It was 37.8% and 54.4% for patients with FPG < 200 mg/dl and FPG > or = 200 mg/dl, respectively, 24.1% for those treated with diet, 51.4% for those treated with oral hypoglycemic agent and 80.7% for those treated with insulin. As a result, it was found that the proportion of death certificates that mentioned diabetes was related to the accompanying complications and the severity of diabetes.(ABSTRACT TRUNCATED AT 250 WORDS)
为确定糖尿病患者所述死因的准确性，我们分析了503份糖尿病患者的死亡证明。这些患者在大阪成人病医疗中心平均随访了9.4年，并于1960年至1984年观察期内死亡。在所检查的证明中，只有213份（42.4%）提到糖尿病，要么作为根本死因，要么作为促成疾病。提到糖尿病的证明比例与根本死因有关；恶性肿瘤为18.7%，脑血管疾病为40.5%，心脏病为46.9%，而肾病为81.8%。女性比例（48.7%）高于男性（39.5%），在心脏病病例中，两性比例存在显著差异。该比例在很大程度上与死亡年份或死亡年龄无关。然而，它与空腹血糖（FPG）水平和治疗类型有关。FPG<200mg/dl和FPG≥200mg/dl的患者分别为37.8%和54.4%，饮食治疗者为24.1%，口服降糖药治疗者为51.4%，胰岛素治疗者为80.7%。结果发现，提到糖尿病的死亡证明比例与伴随并发症和糖尿病严重程度有关。（摘要截短至250字）
