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食物中毒综合征

Food poisoning syndromes.

作者信息

Bishai W R, Sears C L

机构信息

Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

Gastroenterol Clin North Am. 1993 Sep;22(3):579-608.

PMID:8406732
Abstract

Despite our society's advances in sanitation, food preservation, and hygiene, the prevalence of foodborne disease remains high (12.6 million cases per year in the United States). Although there is a constant need for education of food handlers and consumers, there is also a need for continued vigilant monitoring of coastal waters, meat packing facilities, and imported foods. As long as antibiotics are used in poultry and cattle feeds, one can expect the incidence of antibiotic-resistant foodborne pathogens to rise. There are several promising areas of research in the field of foodborne illnesses. Molecular biologists are actively characterizing the genes that enable invasive enteric pathogens such as Salmonella and Yersinia to enter tissues, and the bacterial toxins associated with secretory diarrheas continue to be the subject of intense scrutiny. Epidemiologists are implementing new techniques such as DNA fingerprinting and multilocus enzyme electrophoresis for tracing pathogens in disease outbreaks. Similarly, the use of computers in the food industry facilitates the tracing of contaminated foods. Although the rates of foodborne illness may not decrease significantly during the next decade, we can expect more rapid identification and tracing of outbreaks as well as an improved understanding of the pathogenesis of the foodborne diseases.

摘要

尽管我们的社会在卫生设施、食品保存和卫生方面取得了进步,但食源性疾病的患病率仍然很高(美国每年有1260万病例)。尽管持续需要对食品从业人员和消费者进行教育,但也需要继续对沿海水域、肉类加工设施和进口食品进行严格监测。只要在家禽和牛饲料中使用抗生素,人们就可以预期耐抗生素食源性病原体的发病率会上升。食源性疾病领域有几个很有前景的研究方向。分子生物学家正在积极鉴定使沙门氏菌和耶尔森氏菌等侵袭性肠道病原体能够进入组织的基因,与分泌性腹泻相关的细菌毒素仍然是深入研究的对象。流行病学家正在采用DNA指纹识别和多位点酶电泳等新技术来追踪疾病暴发中的病原体。同样,食品行业中计算机的使用有助于追踪受污染的食品。尽管在未来十年中食源性疾病的发病率可能不会显著下降,但我们可以预期疫情暴发的识别和追踪会更加迅速,并且对食源性疾病发病机制的理解也会有所改善。

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