甘露糖结合蛋白对新型隐球菌与人吞噬细胞结合的影响。
Effect of mannose-binding protein on binding of Cryptococcus neoformans to human phagocytes.
作者信息
Levitz S M, Tabuni A, Treseler C
机构信息
Evans Memorial Department of Clinical Research, Boston, Massachusetts.
出版信息
Infect Immun. 1993 Nov;61(11):4891-3. doi: 10.1128/iai.61.11.4891-4893.1993.
Abstract
The capacity of human peripheral blood monocytes, neutrophils, and monocyte-derived macrophages to bind the yeast Cryptococcus neoformans was increased when the phagocytes were cultured on surfaces containing recombinant human mannose-binding protein. In contrast, soluble mannose-binding protein had no effect on cryptococcal binding by phagocytes.
摘要
当吞噬细胞在含有重组人甘露糖结合蛋白的表面培养时，人类外周血单核细胞、中性粒细胞和单核细胞衍生的巨噬细胞结合新型隐球菌酵母的能力增强。相比之下，可溶性甘露糖结合蛋白对吞噬细胞结合隐球菌没有影响。
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