Ridgway G L
Department of Clinical Microbiology, University College Hospital, London, UK.
J Antimicrob Chemother. 1993 Jul;32 Suppl A:11-6. doi: 10.1093/jac/32.suppl_a.11.
Present treatment schedules for lower genital tract infections are far from ideal. Members of the 4-quinolone antibiotic class are highly active against Neisseria gonorrhoeae, and some of the newer agents are active against Chlamydia trachomatis. Clinical success has been reported with, for example, a single daily dose of ofloxacin for one week. New macrolides are active against C. trachomatis and N. gonorrhoeae. Azithromycin has been shown to be effective in a single oral dose. The role of newer agents in the therapy of bacterial vaginosis is largely unproven, but there are encouraging signs. The importance of attempting to make a firm diagnosis is emphasized.
目前用于治疗下生殖道感染的方案远非理想。4-喹诺酮类抗生素对淋病奈瑟菌具有高度活性，一些新型药物对沙眼衣原体也有活性。例如，据报道每日单次服用氧氟沙星一周可取得临床成功。新型大环内酯类药物对沙眼衣原体和淋病奈瑟菌有活性。阿奇霉素已被证明单次口服有效。新型药物在细菌性阴道病治疗中的作用大多未经证实，但有一些令人鼓舞的迹象。强调了进行明确诊断的重要性。
