Carlson G A, Weintraub S
Department of Child Psychiatry, State University of New York, Stony Brook.
J Affect Disord. 1993 Jul;28(3):143-53. doi: 10.1016/0165-0327(93)90100-x.
A group of offspring at risk for Bipolar Disorder is compared to a Normal Control group whose parents had no psychiatric disorder and a group of offspring at risk for other, non-bipolar psychiatric disorder. Variables examined include childhood attention and behavior problems and psychopathology in young adulthood. Rates of childhood behavior and attention problems, and psychopathology and social/occupational impairment in young adulthood, were higher in the Bipolar Risk group than the Normal Control group, but no higher than in the non-bipolar (Combined Risk) group. Although childhood behavior and attention problems were significantly associated with other psychopathology in all three offspring groups, a unique relationship between childhood problems and young adult mood disorder was found only in the Bipolar Risk group.
将一组有双相情感障碍风险的后代与一个父母没有精神疾病的正常对照组以及一组有其他非双相情感障碍精神疾病风险的后代进行比较。所研究的变量包括童年期的注意力和行为问题以及青年期的精神病理学。双相情感障碍风险组的童年期行为和注意力问题发生率以及青年期的精神病理学和社会/职业障碍发生率高于正常对照组，但不高于非双相情感障碍（综合风险）组。尽管在所有三个后代组中，童年期行为和注意力问题都与其他精神病理学显著相关，但仅在双相情感障碍风险组中发现了童年期问题与青年期情绪障碍之间的独特关系。
