Shaver E G, Rebsamen S L, Yachnis A T, Sutton L N
Department of Neurosurgery, Children's Hospital of Philadelphia, Pennsylvania.
J Neurosurg. 1993 Nov;79(5):769-73. doi: 10.3171/jns.1993.79.5.0769.
Sinus histiocytosis with massive lymphadenopathy was first described in 1969 by Rosai and Dorfman. The typical clinical characteristics of this disease include painless cervical lymphadenopathy, fever, and weight loss. The condition can present with an extranodal mass in about 25% of patients, and isolated masses without lymph node involvement occur rarely. The authors describe a 5-year-old boy with cavernous sinus syndrome due to an isolated extranodal form of sinus histiocytosis with massive lymphadenopathy in the temporal fossa. Several cases of this disease involving the central nervous system are reviewed. The histopathological and magnetic resonance imaging characteristics are discussed.
伴有巨大淋巴结病的窦性组织细胞增生症于1969年由罗萨伊和多尔夫曼首次描述。该疾病的典型临床特征包括无痛性颈部淋巴结病、发热和体重减轻。约25%的患者可出现结外肿块，而无淋巴结受累的孤立肿块很少见。作者描述了一名5岁男孩，因颞窝孤立性结外形式的伴有巨大淋巴结病的窦性组织细胞增生症而出现海绵窦综合征。回顾了几例累及中枢神经系统的该疾病病例。讨论了组织病理学和磁共振成像特征。
