Eiras Josie da Costa, Schettini Antônio Pedro Mendes, Lima Livia Lima de, Tubilla Liana Hortência Miranda, Oliveira Rosa Maria Libório de
Alfredo da Matta Foundation, Manaus, AM, Brazil.
An Bras Dermatol. 2010 Sep-Oct;85(5):687-90. doi: 10.1590/s0365-05962010000500014.
Rosai-Dorfman disease, otherwise known as sinus histiocytosis with massive lymphadenopathy, is a non-Langerhans cell histiocytosis with a benign course and unknown etiology. It was described in 1969 as a painless cervical lymph node enlargement in association with fever, weight loss and sweating. Extranodal disease has been reported in 43% of cases, with involvement of multiple organs. Purely extranodal Rosai-Dorfman disease has been already reported, including forms restricted to the skin. This paper reports a case of purely cutaneous Rosai-Dorfman disease, which is of interest in view of the rarity of this condition.
罗萨伊-多夫曼病，又称伴巨大淋巴结病的窦性组织细胞增多症，是一种非朗格汉斯细胞组织细胞增多症，病程良性，病因不明。1969年，它被描述为一种无痛性颈部淋巴结肿大，伴有发热、体重减轻和出汗。43%的病例报告有结外病变，累及多个器官。纯结外罗萨伊-多夫曼病已有报道，包括局限于皮肤的类型。本文报告一例纯皮肤型罗萨伊-多夫曼病，鉴于这种情况的罕见性，该病例具有一定意义。
