在角叉菜胶诱导的肉芽肿中，由花生四烯酸转化而来的血栓素B2 。
Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma.
作者信息
Chang W C, Murota S, Tsurufuji S
出版信息
Prostaglandins. 1977 Jan;13(1):17-24. doi: 10.1016/0090-6980(77)90038-7.
PMID:841103
Abstract
A main product (PI) transformed from arachidonic acid in carrageenin-induced granuloma in rats was structurally analysed. PI was converted to a more polar substance by the reduction with sodium borohydride. On the basis of the data on gas chromatography-mass spectrometry, its structure was identified with the hemiacetal derivative of 8-(1-hydroxy-3-oxopropyl)-9,12-heptadecadienoic acid (Thromboxane B2).
摘要
对在角叉菜胶诱导的大鼠肉芽肿中由花生四烯酸转化而来的一种主要产物（PI）进行了结构分析。PI通过硼氢化钠还原转化为一种极性更强的物质。基于气相色谱 - 质谱数据，其结构被鉴定为8 -（1 - 羟基 - 3 - 氧代丙基）- 9,12 - 十七碳二烯酸（血栓素B2）的半缩醛衍生物。
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