Dohle G R, Zwartendijk J, Van Krieken J H
Department of Urology, State University Leiden, The Netherlands.
J Urol. 1993 Nov;150(5 Pt 1):1518-20. doi: 10.1016/s0022-5347(17)35833-0.
We report 2 cases of urogenital malacoplakia and discuss the problems associated with diagnosing and treating this rare disease. In 1 case extensive pelvic disease was successfully controlled with ciprofloxacin. In the other case the malacoplakia was localized in the distal ureter and was initially mistaken for urothelial carcinoma. Nephrectomy was performed due to persistent ureteral obstruction and renal dysfunction. In the management of urogenital malacoplakia it seems essential that urinary tract infections be effectively treated. The new fluoroquinolones appear to be potentially successful in managing this disorder due to their high uptake of macrophages.
我们报告了2例泌尿生殖系统软斑病，并讨论了与诊断和治疗这种罕见疾病相关的问题。1例广泛盆腔病变患者经环丙沙星治疗后病情得到成功控制。另1例软斑病局限于输尿管远端，最初被误诊为尿路上皮癌。由于持续的输尿管梗阻和肾功能不全，患者接受了肾切除术。在泌尿生殖系统软斑病的治疗中，有效治疗尿路感染似乎至关重要。新型氟喹诺酮类药物因其在巨噬细胞中的高摄取率，在治疗这种疾病方面似乎可能取得成功。
