Anti leukemia activity (L1210) of 6-mercaptopurine and its metallo complexes in mice.
作者信息
Skinner S M, Lewis R W
出版信息
Res Commun Chem Pathol Pharmacol. 1977 Jan;16(1):183-6.
PMID:841179
Abstract
Six-mercaptopurine in the free form and complexed with Pt, Pd, or Bi metals was used at various dosage levels to treat L1210 leukemia in mice. Anticarcinogenic activity was shown by six-mercaptopurine and the Pd and Bi complexes, inactivity by the Pt complex, and toxicity by the highest dosage level of six-mercaptopurine.
摘要
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