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对阿根廷民间医学中使用的植物进行抗菌活性筛选。

Screening of plants used in Argentine folk medicine for antimicrobial activity.

作者信息

Anesini C, Perez C

机构信息

Catedra de Farmacologia, Facultad de Odontologia, Universidad de Buenos Aires, Argentina.

出版信息

J Ethnopharmacol. 1993 Jun;39(2):119-28. doi: 10.1016/0378-8741(93)90027-3.

DOI:10.1016/0378-8741(93)90027-3
PMID:8412245
Abstract

Screening of 132 extracts from Argentine folk-medicinal plants for antimicrobial activity has been conducted using a penicillin G resistant strain of Staphylococcus aureus, Escherichia coli and Aspergillus niger as test microorganisms. Cephazolin, ampicillin and miconazole were used as standard antibiotics and concentration-response curves were obtained using the agar-well diffusion method. Boiling water extracts of plant materials were tested and 12 species were active against Staphylococcus aureus, whereas 10 were effective against Escherichia coli and 4 against Aspergillus niger. Tabebuia impetiginosa bark, Achyrocline sp. aerials parts, Larrea divaricata leaves, Rosa borboniana flowers, Punica granatum fruit pericarp, Psidium guineense fruit pericarp, Lithrea ternifolia leaves and Allium sativum bulbs produced some of the more active extracts.

摘要

利用一株对青霉素G耐药的金黄色葡萄球菌、大肠杆菌和黑曲霉作为测试微生物,对132种阿根廷民间药用植物提取物进行了抗菌活性筛选。使用头孢唑林、氨苄西林和咪康唑作为标准抗生素,并采用琼脂孔扩散法获得浓度-反应曲线。对植物材料的沸水提取物进行了测试,有12种植物对金黄色葡萄球菌有活性,10种对大肠杆菌有效,4种对黑曲霉有效。破布木树皮、牛膝菊地上部分、拉瑞阿多枝灌木叶、波旁蔷薇花、石榴果皮、几内亚番石榴果皮、三叶莉石楠叶和大蒜鳞茎产生了一些活性更强的提取物。

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