Desta B
School of Pharmacy, Addis Ababa University, Ethiopia.
J Ethnopharmacol. 1993 Jun;39(2):129-39. doi: 10.1016/0378-8741(93)90028-4.
A total of 315 extracts/fractions from 63 traditionally used Ethiopian plants were subjected to antimicrobial screening using known strains of Staphylococcus aureus, Salmonella gallinarum, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa, Klebsiella pneumoniae and Candida albicans. The agar plate well-diffusion method was used at a sample concentration of 1000 micrograms/ml; it was found that all of the plants showed activity against one or more of the microorganism(s). Direct aqueous extracts from six plants were found to be active against all of the test organisms. These findings confirm traditional therapeutic claims for aqueous dosage forms of these herbs. The relative susceptibility of the test organisms to the five types of extracts/fractions indicated a decreasing rank order of: S. aureus, P. aeruginosa, C. albicans, S. gallinarum, E. coli, K. pneumoniae and P. vulgaris.
使用金黄色葡萄球菌、鸡沙门氏菌、大肠杆菌、普通变形杆菌、铜绿假单胞菌、肺炎克雷伯菌和白色念珠菌的已知菌株，对来自63种埃塞俄比亚传统药用植物的总共315种提取物/馏分进行了抗菌筛选。采用琼脂平板打孔扩散法，样品浓度为1000微克/毫升；结果发现，所有植物都对一种或多种微生物表现出活性。发现六种植物的直接水提取物对所有测试微生物均有活性。这些发现证实了这些草药水剂型的传统治疗功效。测试微生物对五种提取物/馏分的相对敏感性表明其敏感性从高到低依次为：金黄色葡萄球菌、铜绿假单胞菌、白色念珠菌、鸡沙门氏菌、大肠杆菌、肺炎克雷伯菌和普通变形杆菌。
