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用于冠状动脉搭桥术的胃网膜右动脉。血流特性和尺寸评估。

Right gastroepiploic artery used for coronary artery bypass grafting. Evaluation of flow characteristics and size.

作者信息

Mills N L, Hockmuth D R, Everson C T, Robart C C

机构信息

Mills Cardiovascular, New Orleans, La.

出版信息

J Thorac Cardiovasc Surg. 1993 Oct;106(4):579-85; discussion 586.

PMID:8412249
Abstract

Questions remain concerning the physiologic capabilities of the right gastroepiploic artery as a bypass graft in the clinical setting. Our last 90 consecutive pedicle right gastroepiploic artery grafts were prepared with intraluminal papaverine and verapamil. Our series comprised 81 male and 9 female patients with average body surface areas of 1.92 m2. Ages ranged from 11 to 79 years (mean 57.2 years). A second to fourth revascularization was undertaken in 32 patients (35.5%). The following arteries were bypassed: posterior descending artery, 63; right coronary artery, 23; distal right, 4; circumflex, 2; left anterior descending, 1; and diagonal, 1. Free flow rates ranged from 42 to 660 ml/min (mean 179.96 ml/min). Internal diameters measured 1.5 to 4.0 mm (mean 2.20 mm) at the anastomotic sites. Pedicle lengths ranged from 16 to 26 cm (mean 19.2 cm). Inotropic support was required in 11 patients (12%) and had no adverse effects on right gastroepiploic artery grafts. There were 2 hospital deaths (2.2%). Angina has recurred in 6 patients. One patient with cardiomyopathy required transplantation 2 years after coronary bypass grafting. Repeat angiography showed widely patent grafts in 18 patients and generalized narrowing in 4 grafts. In only 2 patients of our total experience has right gastroepiploic artery grafting been aborted because of inadequate conduit size. One right gastroepiploic artery had visible atherosclerosis. This study shows that distal right gastroepiploic artery sizes are comparable with sizes of target coronary arteries. However, neither flow nor size is as consistent when compared with internal thoracic artery grafts. Higher flow rates are related to graft anatomic characteristics and larger body surface areas. Spasm, secondary to harvest in these vasoreactive grafts, can be managed appropriately by intraluminal vasodilating drugs. However, use of the right gastroepiploic artery should be avoided in a setting with possible competition of flow.

摘要

在临床环境中,关于胃网膜右动脉作为旁路移植血管的生理功能仍存在一些问题。我们最近连续进行的90例带蒂胃网膜右动脉移植手术均使用了腔内罂粟碱和维拉帕米。我们的病例系列包括81例男性和9例女性患者,平均体表面积为1.92平方米。年龄范围为11至79岁(平均57.2岁)。32例患者(35.5%)进行了二次至四次血运重建。以下动脉接受了旁路移植:后降支动脉63例;右冠状动脉23例;右冠状动脉远端4例;回旋支2例;左前降支1例;对角支1例。自由血流率范围为42至660毫升/分钟(平均179.96毫升/分钟)。吻合部位的内径为1.5至4.0毫米(平均2.20毫米)。带蒂长度范围为16至26厘米(平均19.2厘米)。11例患者(12%)需要使用正性肌力药物支持,且对胃网膜右动脉移植血管无不良影响。有2例医院死亡病例(2.2%)。6例患者心绞痛复发。1例心肌病患者在冠状动脉旁路移植术后2年需要进行心脏移植。重复血管造影显示18例患者的移植血管广泛通畅,4例移植血管普遍狭窄。在我们的全部病例中,只有2例患者因移植血管管径不足而中止胃网膜右动脉移植手术。1例胃网膜右动脉可见动脉粥样硬化。本研究表明,胃网膜右动脉远端的管径与目标冠状动脉的管径相当。然而,与胸廓内动脉移植血管相比,血流和管径都不太稳定。较高的血流率与移植血管的解剖特征和较大的体表面积有关。在这些血管反应性移植血管中,由于取材引起的痉挛可以通过腔内血管扩张药物进行适当处理。然而,在可能存在血流竞争的情况下,应避免使用胃网膜右动脉。

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