Fass J, Bares R, Staude M, Schumpelick V
Chirurgische Klinik der RWTH Aachen.
Leber Magen Darm. 1993 Sep;23(5):194, 197-203.
68 disease free patients were investigated prospectively after jejunal gastric replacement [jejunal interposition (JI): n = 40; Roux en Y reconstruction (RY): n = 28]. Used function tests were: scintigraphic emptying studies, hydrogen breath test, hepatobiliary sequential scintigraphy, oral glucose tolerance test, and upper intestinal manometry with 5 measuring ports (times of investigation: 6-12. week and > 1 year postoperatively). Patients with JI showed a better weight gain (p = 0.001), a lower reflux rate (p = 0.01), a slower orocecal transit time (p = 0.05), a prompter bile flow after meal stimulation (p = 0.02), and lower peak glucose levels (p = 0.001). The emptying patterns of the different gastric substitutes were not different. A higher incidence of retrograde contractions in RY and a electromechanical coordination between duodenum and gastric substitute in JI were detected. We conclude that the postoperative function of the jejunal gastric substitute does not depend on it's emptying pattern or volume but on the motility patterns of the entire intestinal tract which seem to be strongly influenced by the choice of the jejunal reconstruction.
对68例无疾病患者在空肠代胃术后进行前瞻性研究[空肠间置术(JI):n = 40;Roux - en - Y重建术(RY):n = 28]。所采用的功能测试包括:闪烁扫描排空研究、氢呼气试验、肝胆动态闪烁扫描、口服葡萄糖耐量试验以及使用5个测量端口的上消化道测压(研究时间:术后6 - 12周和>1年)。JI患者体重增加更明显(p = 0.001),反流率更低(p = 0.01),口盲传输时间更慢(p = 0.05),餐后胆汁流动更快(p = 0.02),且血糖峰值水平更低(p = 0.001)。不同胃替代物的排空模式无差异。检测到RY中逆行收缩发生率更高,JI中十二指肠与胃替代物之间存在电机械协调性。我们得出结论,空肠代胃术后的功能不取决于其排空模式或容量,而是取决于整个肠道的运动模式,而这似乎受空肠重建方式的强烈影响。