Chaulet J F, Robet Y, Prevosto J M, Grelaud G, Renard C, Bellemin-Magninot P, Lemontey Y
Hôpital d'Instruction des Armées Desgenettes, Services pharmaceutiques et chimiques, Lyon.
Med Trop (Mars). 1993 Apr-Jun;53(2):241-51.
Field malaria studies require often the on site detection of chloroquine in urine for monitoring chemoprophylaxis and treatment compliance, investigating drug-use patterns and screening prospective subjects for in vitro and in vivo chemosensitivity tests. The field adapted methods are described, analytical characteristics are compared and different approaches to field adapted assay of chloroquine are discussed.
现场疟疾研究常常需要对尿液中的氯喹进行现场检测,以监测化学预防和治疗依从性、调查药物使用模式以及为体外和体内化学敏感性测试筛选潜在受试者。本文描述了适用于现场的方法,比较了分析特性,并讨论了氯喹现场适应性检测的不同方法。