Tully J G, Whitcomb R F, Clark H F, Williamson D L
Science. 1977 Mar 4;195(4281):892-4. doi: 10.1126/science.841314.
A spiroplasma recovered from allantoic fluids of chick embryos infected with the tick-derived suckling mouse cataract agent was grown in continuous passage on a new artificial culture medium. The cultured organisms induced typical ocular and other disease symptoms in susceptible animals, and were reisolated from involved host tissues. Although spiroplasmas have been previously recognized as plant and insect pathogens, this is the first spiroplasma shown to multiply at 37 degrees C and to be pathogenic for vertebrates.
从感染蜱传乳鼠白内障病原体的鸡胚尿囊液中分离出的一种螺旋体，在一种新的人工培养基上连续传代培养。培养的微生物在易感动物中引发典型的眼部和其他疾病症状，并从受累的宿主组织中再次分离出来。尽管螺旋体此前已被确认为植物和昆虫病原体，但这是首次发现能在37摄氏度下繁殖并对脊椎动物致病的螺旋体。
