Butler L A, Karp T, McCance K L, Ward R M
Neonatal Netw. 1993 Oct;12(7):31-5.
Accuracy of glucose values is crucial in the management of the critically ill neonate. Sampling for these values may be obtained from an umbilical artery catheter (UAC), but dextrose solutions infused through these catheters may contaminate samples obtained for glucose determination. An in vitro study was conducted to evaluate the effect of blood withdrawal amount and normal saline irrigation on the accuracy of glucose measurements obtained from a UAC. Methods included randomization of blood withdrawal amounts and irrigation with normal saline solution prior to obtaining the blood for glucose measurement. Two hundred and eighty glucose samples were obtained. Results revealed a significant difference between measured and baseline glucose values for all withdrawal amounts and varying flush volumes. This inability to approximate the baseline glucose values could mean that a UAC sample may not reflect the neonate's actual glucose value.
血糖值的准确性在危重新生儿的管理中至关重要。这些数值的采样可通过脐动脉导管（UAC）获取，但通过这些导管输注的葡萄糖溶液可能会污染用于血糖测定的样本。进行了一项体外研究，以评估采血总量和生理盐水冲洗对从脐动脉导管获得的血糖测量准确性的影响。方法包括在采集用于血糖测量的血液之前，随机设定采血总量并用生理盐水进行冲洗。共获取了280份血糖样本。结果显示，所有采血总量和不同冲洗量下，测量的血糖值与基线血糖值之间存在显著差异。无法近似基线血糖值可能意味着脐动脉导管样本可能无法反映新生儿的实际血糖值。
