Ferri L, Bertelli G, Innocenti S, Di Grancio R, Tinagli F
UO Anestesia e Rianimazione, USSL 26, Portoferraio (Livorno).
Minerva Anestesiol. 1993 Jun;59(6):317-20.
After having considered the physiopathological mechanism of shivering, the authors have estimated in a randomised study the effects of the resolution of shivering by nefopam hydrochloride. This drug a dose of 0.20 mg/kg resolved the symptoms in 100% of cases and the placebo hasn't resolved a case so that case it also obtained the same effects. The authors have proved the efficacy of the nefopam hydrochloride in the control of postoperative shivering in the recommended dose.
在考虑了寒战的生理病理机制后，作者在一项随机研究中评估了盐酸奈福泮缓解寒战的效果。该药物剂量为0.20mg/kg时，100%的病例症状得到缓解，而安慰剂无一例症状缓解，因此它也获得了相同的效果。作者已证明盐酸奈福泮在推荐剂量下控制术后寒战的有效性。
