Ferri L, Bertelli G, Innocenti S, Di Grancio R, Tinagli F
UO Anestesia e Rianimazione, USSL 26, Portoferraio (Livorno).
Minerva Anestesiol. 1993 Jun;59(6):317-20.
After having considered the physiopathological mechanism of shivering, the authors have estimated in a randomised study the effects of the resolution of shivering by nefopam hydrochloride. This drug a dose of 0.20 mg/kg resolved the symptoms in 100% of cases and the placebo hasn't resolved a case so that case it also obtained the same effects. The authors have proved the efficacy of the nefopam hydrochloride in the control of postoperative shivering in the recommended dose.