Lewczuk J, Palka P, Reczuch K, Piszko P, Spikowski J, Wrabec K
Oddziału Internistyczno-Kardiologicznego Wojewódzkiego Szpitala Specjalistycznego, Wrocławiu.
Pol Tyg Lek. 1993;48(14-15):324-6.
Both oral and intravenous ipratropium bromide were assessed clinically, electrocardiographically and electrophysiologically in 15 patients with symptomatic bradycardia, aged between 32 and 79 years. Ipratropium bromide administered intravenously accelerated heart rate by more than 30% in the majority of patients. Electrophysiologically it normalized conduction time and sinus node response. Electrophysiological studies did not enable to foreseen the efficiency of oral form which may be useful in the treatment of symptomatic bradycardia in increased parasympathetic tone and both mild, and moderate sinus node insufficiency.
对15例年龄在32至79岁之间有症状性心动过缓的患者进行了临床、心电图和电生理方面的评估，给予其口服和静脉注射异丙托溴铵。大多数患者静脉注射异丙托溴铵后心率加快超过30%。在电生理方面，它使传导时间和窦房结反应恢复正常。电生理研究无法预测口服剂型的疗效，口服剂型可能对治疗副交感神经张力增加以及轻度和中度窦房结功能不全所致的症状性心动过缓有用。
