Urban J
Katedra i Klinika Chirurgii Urazowej AM, Wrocławiu.
Polim Med. 1993;23(1-2):55-67.
In the last decade hundreds of the knee cruciate ligaments prostheses have been implanted in patients. Late follow up results of this kind of operations are under further discussion and therefore research of such implants of the cruciate ligaments are still on the way. The author has evaluated 5 kinds of polyester ACL polyester prosthesis Trevira of the same mechanical properties with a difference only in texture. He implanted them in place of primarily removed ACL in piglets of 20-30 kg and in rabbits into dorsal muscles to evaluate their biocompatibility. After 3 and 6 months period the autopsy of piglets has been performed and macroscopic image, histologic examination and X-ray image has been evaluated. The autopsy of rabbits has been performed after 14 days and 3 months. All examination described above proved the high biocompatibility of polyester prostheses. Quite significant quantitative differences in fibro-connective tissue ingrowing into the different implants of their intraarticular, intraosseous and extraarticular portion. Prostheses of loose texture have very good connective tissue ingrowing ability and seem to be more useful in cruciate ligaments replacement. Especially useful they can be in augmentation of the autogenic tissues because of their better junction with the implant, so they created functional unit. Increased amount of connective fibre tissue ingrowing the implant can be the factor of diminishing its degradation and negative influence of the knee articulation.
在过去十年中，已有数百例膝关节交叉韧带假体被植入患者体内。此类手术的后期随访结果仍在进一步讨论中，因此对交叉韧带这类植入物的研究仍在进行。作者评估了5种具有相同机械性能、仅质地不同的聚酯前交叉韧带（ACL）聚酯假体Trevira。他将它们植入20 - 30千克仔猪体内，取代最初切除的ACL，并植入兔子背部肌肉中，以评估其生物相容性。在3个月和6个月后，对仔猪进行解剖，并评估宏观图像、组织学检查和X射线图像。在14天和3个月后对兔子进行解剖。上述所有检查均证明聚酯假体具有高生物相容性。在其关节内、骨内和关节外部分的不同植入物中，长入的纤维结缔组织存在相当显著的定量差异。质地疏松的假体具有非常好的结缔组织长入能力，似乎在交叉韧带置换中更有用。由于它们与植入物的结合更好，可以形成功能单元，因此在自体组织增强方面可能特别有用。长入植入物的结缔纤维组织数量增加可能是减少其降解以及膝关节负面影响的一个因素。
