Valk P E, Laxer K D, Barbaro N M, Knezevic S, Dillon W P, Budinger T F
Department of Radiology, University of California, San Francisco.
Radiology. 1993 Jan;186(1):55-8. doi: 10.1148/radiology.186.1.8416586.
Eleven patients with medically refractory partial seizures underwent positron emission tomography (PET) with a 600-crystal tomograph and fluorine-18 fluorodeoxyglucose. All patients had been selected for temporal lobe resection, and the side of the epileptogenic focus had been demonstrated with electroencephalography (EEG). Only patients in whom structural lesions had been excluded with magnetic resonance (MR) imaging were studied. Ten of 11 patients were found to have temporal cortical hypometabolism on the same side as the focal abnormality that was demonstrated with EEG. In two patients, PET showed hypometabolism in the mesial temporal cortex only. There were no incorrectly lateralizing PET results. MR imaging showed an abnormality in the corresponding temporal lobe in seven patients. In one patient, both PET and MR images were normal. All patients underwent anterior temporal resection, and histologic examination of resected tissue showed mesial temporal sclerosis in all cases.
11例药物难治性部分性癫痫患者接受了使用600晶体断层扫描仪和氟-18氟脱氧葡萄糖的正电子发射断层扫描（PET）。所有患者均被选作颞叶切除术，且癫痫病灶侧已通过脑电图（EEG）证实。仅对经磁共振（MR）成像排除结构性病变的患者进行了研究。11例患者中有10例在与EEG显示的局灶性异常同侧出现颞叶皮质代谢减低。2例患者PET仅显示内侧颞叶皮质代谢减低。PET定位结果均无错误。7例患者MR成像显示相应颞叶有异常。1例患者PET和MR图像均正常。所有患者均接受了前颞叶切除术，切除组织的组织学检查显示所有病例均有内侧颞叶硬化。
