Fujii M, Adachi S, Shimizu T, Hirota S, Sako M, Kono M
Department of Radiology, Kobe University School of Medicine, Japan.
J Thorac Imaging. 1993 Winter;8(1):54-62.
Interstitial lung disease (ILD) is a frequent manifestation of rheumatoid arthritis (RA), and it has a close bearing on the prognosis of RA patients. Computed tomography (CT) has been shown to be excellent for the diagnosis of diffuse lung disease. In this study chest radiographs and high-resolution CT (HRCT) scans were obtained in 91 patients with RA to evaluate their ILD precisely. By HRCT 43 patients could be diagnosed as having interstitial pneumonitis (IP), and 5 could be diagnosed as having bronchiolitis. The remaining 43 patients were normal by HRCT. Chest radiographic findings were consistent with the HRCT findings in approximately 50% of patients with IP. HRCT was superior to chest radiographs for the detection of early interstitial changes. The histogram of HRCT values might be a useful adjunct to HRCT diagnosis by adding some degree of objectivity. HRCT is useful for the diagnosis of ILD in patients with RA.
间质性肺疾病（ILD）是类风湿关节炎（RA）的常见表现，且与RA患者的预后密切相关。计算机断层扫描（CT）已被证明在诊断弥漫性肺疾病方面表现出色。在本研究中，对91例RA患者进行了胸部X线片和高分辨率CT（HRCT）扫描，以精确评估他们的ILD。通过HRCT，43例患者可被诊断为间质性肺炎（IP），5例可被诊断为细支气管炎。其余43例患者的HRCT检查结果正常。胸部X线片表现与约50%的IP患者的HRCT结果一致。HRCT在检测早期间质改变方面优于胸部X线片。HRCT值直方图通过增加一定程度的客观性，可能是HRCT诊断的有用辅助手段。HRCT对RA患者ILD的诊断很有用。
