Groos E B, Mannis M J, Brumley T B, Huntley A C
Department of Ophthalmology, University of California, Davis 95618.
Am J Ophthalmol. 1993 Jan;115(1):42-5. doi: 10.1016/s0002-9394(14)73522-6.
We treated a 56-year-old man who had acanthosis nigricans associated with gastric adenocarcinoma and involving the axillae, hands, feet, anus, soft palate, and eyes. The patient developed epiphora from occlusion of the canaliculi with papillomatous lesions. Recognition of the ocular signs of this paraneoplastic syndrome may indicate to the ophthalmologist that the patient should have a thorough oncologic examination.
我们治疗了一名56岁男性，他患有与胃腺癌相关的黑棘皮病，病变累及腋窝、手部、足部、肛门、软腭和眼睛。患者因乳头状病变阻塞泪小管而出现溢泪。眼科医生认识到这种副肿瘤综合征的眼部体征，可能提示该患者应进行全面的肿瘤学检查。
