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基层医疗环境中低风险女性的衣原体沙眼衣原体无症状感染及预测标准。

Asymptomatic Chlamydia trachomatis infection and predictive criteria among low-risk women in a primary care setting.

作者信息

Tosun Ilknur, Cihanyurdu Meral, Kaklikkaya Nese, Topbas Murat, Aydin Faruk, Erturk Murat

机构信息

Department of Microbiology and Clinical Microbiology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey.

出版信息

Jpn J Infect Dis. 2008 May;61(3):216-8.

Abstract

The aim of this study was to estimate the prevalence and predictors of Chlamydia trachomatis infection among young adult low-risk women attending either of two inner-city family planning clinics in Trabzon, the most densely populated city in Turkey's Black Sea region. The study group comprised 150 sexually active women attending either of two family planning clinics. Two endocervical swabs were collected from each woman and tested for the presence of C. trachomatis by tissue culture and a commercially available enzyme immunoassay (ELISA). Multivariable logistic regression analysis was used to identify the associations of clinical factors for predicting C. trachomatis infection. C. trachomatis was detected in 19 of the samples (12.7%) by cell culture and in 15 (9.9%) by ELISA. None of the demographic characteristics could be associated with the state of infection, but the women preferring the withdrawal method for contraception accounted for a significantly higher percentage of the C. trachomatis-positive cases than women who used other contraceptive methods. The most frequent signs of cervical infection were vaginal discharge (RR = 4.86, 95% CI 1.60 and 14.79, P = 0.005) and cervical erosion (RR = 3.26, 95% CI 0.97 and 10.90, P = 0.056).

摘要

本研究的目的是估计在土耳其黑海地区人口最密集的城市特拉布宗的两家市中心计划生育诊所就诊的低风险年轻成年女性中沙眼衣原体感染的患病率及预测因素。研究组包括在两家计划生育诊所就诊的150名有性行为的女性。从每位女性采集两份宫颈拭子,通过组织培养和一种市售酶免疫测定法(ELISA)检测沙眼衣原体的存在。采用多变量逻辑回归分析来确定预测沙眼衣原体感染的临床因素之间的关联。通过细胞培养在19份样本(12.7%)中检测到沙眼衣原体,通过ELISA在15份样本(9.9%)中检测到。没有任何人口统计学特征与感染状态相关,但比起使用其他避孕方法的女性,采用体外排精法避孕的女性中沙眼衣原体阳性病例的比例显著更高。宫颈感染最常见的体征是阴道分泌物增多(相对危险度=4.86,95%可信区间为1.60至14.79,P=0.005)和宫颈糜烂(相对危险度=3.26,95%可信区间为0.97至10.90,P=0.056)。

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