Knapp W H, Bentrup A, Ohlmeier H
Institute of Nuclear Medicine, University Hospital, Ruhr-Universität Bochum, Bad Oeynhausen, Federal Republic of Germany.
Eur J Nucl Med. 1993 Jan;20(1):80-2. doi: 10.1007/BF02261250.
The aetiology of cardiac dysfunction caused by sarcoid granulomatous inflammation may be difficult to clarify, and the potential of imaging methods is limited. We report on a patient who presented with acute biventricular decompensation. Pulmonary sarcoidosis was confirmed after hospitalization. Four weeks after the initiation of corticosteroid treatment, scintigraphy with indium-111-labelled antimyosin antibody Fab fragments (AMAB) revealed distinct activity accumulation in major parts of the left ventricular wall (heart-lung ratio: 1.6) 72 h following injection. There may be a role for AMAB scintigraphy in the early detection of cardiac sarcoidosis.
