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6至14周龄小猫去势的麻醉技术。

Anesthetic techniques for neutering 6- to 14-week-old kittens.

作者信息

Faggella A M, Aronsohn M G

机构信息

Massachusetts Society for the Prevention of Cruelty to Animals, Angell Memorial Animal Hospital, Boston 02130.

出版信息

J Am Vet Med Assoc. 1993 Jan 1;202(1):56-62.

PMID:8420907
Abstract

Forty-eight male and 48 female 6- to 14-week-old kittens were neutered by use of 4 anesthetic protocols. Preanesthetic disposition, depth of sedation, loss of resistance to handling, induction quality, induction time, sternal and stand times, and recovery quality were evaluated. Analgesia and muscle relaxation without supplemental inhalational anesthetics were evaluated in male kittens, and the time until extubation was recorded in female kittens. Intramuscular administration of tiletamine/zolazepam (TZ), midazolam/ketamine, atropine/midazolam/ketamine/butorphanol (AMKB), and atropine/midazolam/ketamine/oxymorphone (AMKO) produced rapid sedation and smooth induction into anesthesia. In male kittens, there were no significant differences in sedation, relaxation, induction time, or quality. Tiletamine/zolazepam administration induced the best analgesia, and midazolam/ketamine administration induced the least analgesia for castration. The recovery time in male kittens was longest with TZ and shortest with the opioid groups (AMKB, AMKO). In females, TZ produced significantly faster induction times, but the degree of sedation and relaxation after administration of injectable agents was not significantly different among the groups. More females given TZ could be intubated without supplemental inhalational agents than females in other groups. Extubation time was rapid in all groups, but the times until sternal and standing were significantly longer, and recovery quality was significantly poorer in females given TZ. In kittens given opioids, reversal of the opioid did not shorten recovery time or improve recovery quality.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

48只6至14周龄的雄性小猫和48只雌性小猫通过4种麻醉方案进行绝育。评估了麻醉前状态、镇静深度、对操作的抵抗丧失、诱导质量、诱导时间、胸骨卧位和站立时间以及恢复质量。在雄性小猫中评估了无需补充吸入麻醉剂的镇痛和肌肉松弛情况,并记录了雌性小猫直至拔管的时间。肌肉注射替来他明/唑拉西泮(TZ)、咪达唑仑/氯胺酮、阿托品/咪达唑仑/氯胺酮/布托啡诺(AMKB)和阿托品/咪达唑仑/氯胺酮/羟吗啡酮(AMKO)可产生快速镇静并平稳诱导麻醉。在雄性小猫中,镇静、松弛、诱导时间或质量方面无显著差异。注射替来他明/唑拉西泮诱导的去势镇痛效果最佳,而注射咪达唑仑/氯胺酮诱导的镇痛效果最差。雄性小猫中,TZ组的恢复时间最长,阿片类药物组(AMKB、AMKO)最短。在雌性小猫中,TZ组的诱导时间明显更快,但注射药物后各组的镇静和松弛程度无显著差异。与其他组的雌性小猫相比,接受TZ的更多雌性小猫无需补充吸入麻醉剂即可插管。所有组拔管时间都很快,但接受TZ的雌性小猫直至胸骨卧位和站立的时间明显更长,恢复质量明显更差。在给予阿片类药物的小猫中,阿片类药物的逆转并未缩短恢复时间或改善恢复质量。(摘要截断于250字)

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