脂蛋白(a)及其在闭塞性血管疾病中的作用。
Lipoprotein(a) and its role in occlusive vascular disease.
作者信息
Tennant M, McGeachie J K
机构信息
Department of Anatomy and Human Biology, University of Western Australia, Nedlands.
出版信息
Ann R Coll Surg Engl. 1993 Jan;75(1):3-7.
An increased serum level of lipoprotein(a) (LP(a)) is acknowledged as an independent risk factor for occlusive vascular disease, especially atherosclerosis. Recently, a considerable amount of data has been produced on the structure and functional relationships between Lp(a) and the primary cellular interactions of atherosclerosis. In this review we discuss the structure and function of Lp(a) with specific reference to its role in the proposed mechanisms of atherosclerosis.
血清脂蛋白(a) [Lp(a)]水平升高被公认为是闭塞性血管疾病尤其是动脉粥样硬化的独立危险因素。最近，关于Lp(a)与动脉粥样硬化主要细胞相互作用之间的结构和功能关系，已经产生了大量数据。在这篇综述中，我们将讨论Lp(a)的结构和功能，并特别提及它在动脉粥样硬化发病机制中的作用。
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