Man'kovskii N B, Vanishtok A B, Lizogub V G
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(1):51-5.
As a rule, in patients with idiopathic parkinsonism the cerebral volume blood flow is decreased in the parietal lobes. Patients with vascular parkinsonism display a decreased blood flow in the frontal and occiptial lobes, more so in the parietal. An inhalation of pure oxygen in the control group of normals decreased the general cerebral blood flow, while in parkinsonic patients it increased it only in the parietal lobes. Treatment with l-dopa regularly and significantly increased the general and regional cerebral blood flow.
通常情况下,特发性帕金森病患者的顶叶脑血流量会减少。血管性帕金森病患者的额叶和枕叶血流量减少,顶叶更为明显。正常对照组吸入纯氧会使全脑血流量减少,而帕金森病患者吸入纯氧仅使顶叶血流量增加。左旋多巴治疗可使全脑和局部脑血流量有规律且显著增加。