Rodriguez G, Cogorno P, Gris A, Marenco S, Mesiti C, Nobili F, Rosadini G
Institute of Neurophysiopathology, University of Genova, Italy.
J Cereb Blood Flow Metab. 1989 Jun;9(3):410-6. doi: 10.1038/jcbfm.1989.60.
Regional CBF (rCBF) was evaluated by the 133Xe inhalation method in 60 neurologically normal patients (30 men and 30 women) and hemispheric and regional values were correlated with anxiety measurements collected by a self-rating questionnaire before and after the examination. Statistically significant negative correlations between rCBF and anxiety measures were found. rCBF reduction for high anxiety levels is in line with results previously reported by others and could be related to lower performance levels for moderately high anxiety scores as those reported in the present population. This could perhaps be explained by rearrangement of flow from cortical zones to deeper areas of the brain, classically known to be implicated in the control of emotions. However, these results should be interpreted cautiously, since they were obtained in patients and not in normal subjects.
采用吸入¹³³Xe法对60例神经功能正常的患者（30名男性和30名女性）进行了局部脑血流量（rCBF）评估，并将半球和局部值与检查前后通过自评问卷收集的焦虑测量值进行了相关性分析。发现rCBF与焦虑测量值之间存在统计学上显著的负相关。高焦虑水平下rCBF降低与其他人先前报道的结果一致，可能与本研究人群中中度高焦虑评分时较低的表现水平有关。这或许可以通过血流从皮质区重新分布到大脑深部区域来解释，传统上认为大脑深部区域与情绪控制有关。然而，这些结果应谨慎解释，因为它们是在患者而非正常受试者中获得的。
