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An irradiation-reduced hybrid panel for fine-structure mapping of the Xq28 region in the human genome.

作者信息

Peterlin B, Smahi A, Holvoet-Vermaut L, Heitz D, Dahl N, Hors-Cayla M C

机构信息

INSERM U-12, Hôpital des Enfants-Malades, Paris France.

出版信息

Cytogenet Cell Genet. 1993;62(1):58-9. doi: 10.1159/000133447.

DOI:10.1159/000133447
PMID:8422759
Abstract

Irradiation-reduced somatic cell hybrids containing fragments of the human X chromosome were constructed. Analysis of 16 hybrids that retained the Xq28 region with 12 Xq28-specific markers identified at least six different breakpoints, supporting the order cen-DXS304-DXS374-(DXS33, DXS134, DXS52, DXS15)-RCP-(DXS254, G6PD, F8C)-(DXS115, DXYS64)-qter. The generated panel of hybrids provides a useful tool for fine mapping of probes in the Xq28 region.

摘要

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