McClain W H
Department of Bacteriology, University of Wisconsin, Madison 53706-1567.
FASEB J. 1993 Jan;7(1):72-8. doi: 10.1096/fasebj.7.1.8422977.
Since its theoretical inception, the tRNA molecule has been identified and many of its functions have been described in terms of its structure. However, the molecular basis for the aminoacylation specificity of tRNA has remained largely unsolved until recently, when substantial progress has disclosed fundamental aspects of this process. What we know and would like to know about tRNA identity will be outlined, as will the experimental approaches used in this research.
自其理论提出以来,tRNA分子已被识别,并且其许多功能已根据其结构进行了描述。然而,tRNA氨酰化特异性的分子基础在很大程度上一直未得到解决,直到最近取得了重大进展,揭示了这一过程的基本方面。我们所知道的以及想要了解的关于tRNA身份的信息将被概述,本研究中使用的实验方法也将被概述。