Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
RNA. 2010 Oct;16(10):1865-9. doi: 10.1261/rna.2266510. Epub 2010 Aug 18.
Four recent studies suggest that cleavages of transfer RNAs generate products with microRNA-like features, with some evidence of function. If their regulatory functions were to be confirmed, these newly revealed RNAs would add to the expanding repertoire of small noncoding RNAs and would also provide new perspectives on the coevolution of transfer RNA and messenger RNA.
四项近期研究表明,转移 RNA 的切割产物具有 microRNA 样特征,并具有一些功能证据。如果它们的调节功能得到证实,这些新发现的 RNA 将增加小非编码 RNA 的不断扩大的种类,并且还将为转移 RNA 和信使 RNA 的共同进化提供新的视角。