青蛙公主：非洲爪蟾背腹模式的分子配方 - Suppr

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超能文献

The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus.

作者信息

Sive H L

机构信息

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142.

出版信息

Genes Dev. 1993 Jan;7(1):1-12. doi: 10.1101/gad.7.1.1.

DOI:10.1101/gad.7.1.1

PMID:8422980

Abstract

摘要

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The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus.青蛙公主：非洲爪蟾背腹模式的分子配方

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Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.非洲爪蟾胚胎细胞对激活素和FGF的反应由多个剂量阈值分隔开，且对应于中胚层的不同轴。

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Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo.卵泡抑素与骨形态发生蛋白及其受体复合物的直接结合抑制非洲爪蟾早期胚胎的腹侧和表皮细胞命运。

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The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins.非洲爪蟾短尾相关蛋白启动子被成纤维细胞生长因子（FGF）和低浓度的激活素激活，并被高浓度的激活素和配对型同源域蛋白抑制。

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