Euwer R L, Sontheimer R D
Department of Dermatology, U.T. Southwestern Medical Center, Dallas 75235.
J Invest Dermatol. 1993 Jan;100(1):124S-127S. doi: 10.1111/1523-1747.ep12356896.
Jim Gilliam's research interests throughout his career were forced upon better defining the relationships that exist between the cutaneous and systemic manifestations of the rheumatic diseases. Although the majority of his time was spent studying such relationships in lupus erythematosus patients, he was also intensely interested in dermatomyositis (DM) in this regard as well. He was particularly intrigued with the dissociation of the cutaneous and muscular manifestations of this disorder that occasionally occurs. The term "dermatomyositis siné myositis" has been used in the past to describe patients who present with only the cutaneous manifestations of DM; however, very little published data is available from systematic examinations of such patients. For several reasons, we have preferred the term "amyopathic dermatomyositis" to describe that rare patient who for long periods of time suffers from the classical skin lesions of DM as the only clinically significant manifestation of their disease. In this presentation, we review our own personal experience with a group of six such patients and compare and contrast it to that of other workers who have dealt with this subject over the past two decades.
吉姆·吉列姆在其整个职业生涯中的研究兴趣都集中在更好地界定风湿性疾病的皮肤表现与全身表现之间的关系上。尽管他大部分时间都花在研究红斑狼疮患者的此类关系上，但他在这方面对皮肌炎（DM）也有着浓厚的兴趣。他尤其对这种疾病偶尔出现的皮肤和肌肉表现的分离现象感兴趣。过去曾用“无肌病性皮肌炎”一词来描述仅表现出皮肌炎皮肤症状的患者；然而，关于此类患者的系统检查，公开的数据非常少。出于几个原因，我们更倾向于用“无肌病性皮肌炎”这个术语来描述那些长期患有皮肌炎典型皮肤病变，且这是其疾病唯一具有临床意义表现的罕见患者。在本报告中，我们回顾了我们自己对一组六名此类患者的个人经验，并将其与过去二十年来处理该主题的其他研究者的经验进行比较和对照。
